The Missouri Compromise: Maine is admitted as a free state, Missouri as a slave state (1821), and slavery is prohibited in the remainder of the Louisiana Purchase territory north of 36°30' (southern boundary of Missouri).
James Monroe is re-elected President.
African-American population reaches 1.77 million; total U.S. population is 9.6 million.
Expansion of New England textile mills.
U.S. Army forbids enlistment of black or mulatto soldiers.
Growth of female moral-reform societies begins.